The ThermoBrite Elite from IRIS International is an automated FISH (fluorescence in-situ hybridization) sample preparation platform. A multipurpose automated laboratory assistant for automating the repetitive, manual laboratory protocols used in FISH and other ISH testing for both clinical and research applications, the platform enables meaningful increases in productivity, standardization, and reproducibility. With the increasing rate of adoption of FISH testing as standard protocol for cancer diagnostics development and application, labs performing as few as ten tests per day are requiring a higher level of automation and standardization. An easy-to-use graphic user interface offers standard protocols for blood, urine, or solid tumor FISH procedures or the user can customize protocols for other tests. Twelve slides can be processed per run, with up to ten reagents dispensed and three independent waste ports for selective disposal.