New & Noteworthy

May-June 2014

Immunoaffinity Sample Preparation

Thermo Fisher Scientific

Thermo Scientific Mass Spectrometric Immunoassay (MSIA) pipette tips are a collection of immunoaffinity sample preparation products. Robust MSIA technology delivers a simplified way to enrich target proteins for downstream mass spectrometric analysis. The tips feature a 300 µl pipette tip embedded with a proprietary, highly porous immunoaffinity column that provides increased sensitivity with improved reproducibility and sample throughput. Benefits include enhanced antibody/antigen-binding kinetics that allow enrichment down to very low levels (femtomoles); improved signal-to-noise ratios due to increased specificity and target recovery; fast and flexible sample throughput with manual multichannel or fully automated 96-well processing in less than 30 minutes; and a customizable assay that meets different biomarker research needs. The MSIA DARTs (disposable automation research tips) are compatible with the Versette automated liquid handler, providing immuno-enrichment processing in 96-well format. In addition, the new Thermo Scientific Finnpipette Novus i 8- and 12-channel electronic pipettes (for immuno-precipitation) and adjustable pipette stand are designed to work with MSIA protocols where high sample throughput is not required.

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