A substantial portion of the laboratory director’s role is striking a proper balance between clinical operations and business operations in a progressive manner. Many laboratories are employing advanced billing and accounts receivable systems to not only help gain and track outreach business, but to demonstrate cost savings and profits when seeking approval for new and advanced instrumentation and broader methodologies, in house. Transparent revenue cycle management (RCM) in laboratory outreach can enable expansion in the scope and quality of laboratory services overall, and advanced billing and AR systems help enable this process.