New & Noteworthy

May-June 2014

Chemically-Modified Taq Polymerase

Empirical Bioscience, Part of Fortis Life Sciences

Empirical Bioscience (formerly known as Syzygy Biotech), introduces FlashTaq Hot-Start Taq DNA Polymerase, a chemically-modified Taq polymerase designed to reduce non-specific amplification in PCR. The enzyme offers fewer contamination issues and a fast activation time. Under standard hot start conditions, it can be activated and the enzyme recovers both 5'-3' polymerase and 5'-exonuclease activities within two minutes. FlashTaq's stability and rapid activation time, in addition to the type of modifying reagent that it uses, helps streamline studies. The enzyme in FlashTaq has a reduced risk of contamination because it has been chemically-modified versus antibody-modified; enzymes that are antibody-modified are highly susceptible to contamination from the organism in which they are produced. FlashTaq is useful for PCR in laboratory settings where primer-dimers and contamination are identified problems.

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